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Article

[Analysis of genetic changes in progression of colorectal cancer].

Gan to kagaku ryoho. Cancer & chemotherapy - 1 Jun 1996

Kuroda K, Watatani M, Yoshida T, Ieda S, Shindo K, Yasutomi M

Abstract excerpt

To investigate whether genetic changes of the p53 gene and genetic defects in DNA-mismatch repair systems are involved in progression of colorectal carcinomas (CRCs), we examined loss of heterozygosity (LOH) on 17p and mutations in exon 5 through 8 of the p53 gene as well as replication errors (RER) at four microsatellite loci in DNAs from 108 CRCs at all clinical stages (20 Dukes A, 40 Dukes b, 48 Dukes C). We...

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Identifiers

PMID: 8678562

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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