Article
Are DNA mismatch repair deficiencies responsible for accumulation of genetic alterations in epithelial ovarian cancers?
Cancer genetics and cytogenetics - 15 Jan 2001
Suzuki M, Ohwada M, Saga Y, Saito S, Sato I
Abstract excerpt
To investigate the association of DNA mismatch repair deficiencies in the development and/or progression of epithelial ovarian cancers, the relationship between replication errors (RERs) and genetic alterations in three genes (p53, c-erbB2, K-ras) and loss of heterozygosity (LOH) on 6q27 was investigated in 70 patients with epithelial ovarian cancers. The presence of RERs was examined by PCR using five...
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