Article
Allelic loss of chromosome 17p, mutation of the p53 gene, and microsatellite instability in right- and left-sided colorectal cancer.
Cancer - 15 Apr 1996
Watatani M, Yoshida T, Kuroda K, Ieda S, Yasutomi M
Abstract excerpt
BACKGROUND: Epidemiologic and genetic studies suggest that cancer of the right and left sides of the bowel arise through different mechanisms. To investigate the molecular mechanisms, allelic loss of chromosome 17p, p53 mutations, and microsatellite instability were analyzed in colorectal cancer according to tumor site. METHODS: Using the polymerase chain reaction and single strand conformation polymorphism...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
