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Article

A comparison of the genetic pathways involved in the pathogenesis of three types of colorectal cancer.

The Journal of pathology - 1 Feb 1998

Tomlinson I, Ilyas M, Johnson V, Davies A, Clark G, Talbot I, Bodmer W

Abstract excerpt

Patterns of allele loss (loss of heterozygosity, LOH) have been studied in order to investigate the genetic pathways involved in the pathogenesis of three types of colorectal cancer (CRC): sporadic CRC without replication errors (RER-) (32 cases); sporadic RER+ CRC (23 cases); and ulcerative colitis-associated CRC (UCACRC) (16 cases). Each tumour was assessed for allele loss at ten microsatellite markers which...

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Source

Identifiers

PMID: 9602705
DOI: 10.1002/(SICI)1096-9896(199802)184:2<148::AID-PATH986>3.0.CO;2-M

Genes

APC
DCC

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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