Article
[Colonic cancer: from molecular diagnosis to diagnostic and therapeutic procedure].
La Revue de medecine interne - 1 Jan 1997
Laurent-Puig P, Olschwang S
Abstract excerpt
Studies of tumour cell genetic alterations have demonstrated the existence of two distinct groups of colorectal cancers. The first one is characterised by the existence of hyperploid tumour cells and frequent loss of heterozygosity. These colorectal cancers are the most common. The second one is characterised by the presence of microsatellite instability. Among the most frequent genetic alterations, the loss of...
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