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Article

Differential prognosis of replication error phenotype and loss of heterozygosity in sporadic colorectal cancer.

European journal of cancer (Oxford, England : 1990) - 1 Nov 1999

Massa M J, Iniesta P, González-Quevedo R, de Juan C, Caldés T, Sánchez-Pernaute A, Cerdán J, Torres A J, Balibrea J L, Benito M

Abstract excerpt

Several distinct genetic alterations have been associated with colorectal tumorigenesis. This study investigated the frequency of microsatellite instability, also known as replication error (RER), and loss of heterozygosity (LOH) at six chromosome regions in sporadic colorectal cancer (CRC). Eighty-six tumour and paired normal mucosa samples were included in the study. A polymerase chain reaction (PCR)-based...

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Identifiers

PMID: 10674012
DOI: 10.1016/s0959-8049(99)00158-6

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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