Article
[p53 mutations in sporadic colorectal cancers with microsatellite instability].
Zhonghua yi xue za zhi - 10 Jul 2003
Huang Jian, Zheng Shu, Pan Qiang-rong, Deng Yong-chuan
Abstract excerpt
OBJECTIVE: To study p53 mutation and its association with microsatellite instability (MI)/replication error (RER) in sporadic colorectal cancer. METHODS: Fifty five cases of sporadic colorectal cancer were analyzed for MI/RER by PCR-based silver staining or ABI377 sequencer at following seven separate microsatellite loci: BAT-26, D2S119, D2S123, D3S1293, D8S282, D13S160 and D18S58. p53 mutations at exon 5 - 8...
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