Article
[Microsatellite alterations on chromosome 9p21-22 in sporadic colorectal cancer].
Zhonghua bing li xue za zhi = Chinese journal of pathology - 1 Dec 1999
Zhang Y, Lai M
Abstract excerpt
OBJECTIVE: To study whether alteration of p16 plays an important role in the development of colorectal carcinomas and the relationship between the molecular changes of 9p21-22 chromosome subregion in sporadic colorectal cancers. METHODS: To detect microsatellite instability (MSI) and loss of heterozygosity (LOH) by PCR, denatured-polyacrylamide gel-electrophoresis and silver staining (microsatellite...
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