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Article

Association of restriction fragment-length polymorphisms in the alcohol dehydrogenase 2 gene with alcoholic brain atrophy.

Alcoholism, clinical and experimental research - 1 Feb 1996

Maezawa Y, Yamauchi M, Searashi Y, Takeda K, Mizuhara Y, Kimura T, Toda G, Suzuki H, Sakurai S

Abstract excerpt

Alcohol abuse can induce brain atrophy, but it only occurs in some alcoholics. To investigate whether genetic polymorphism of alcohol-metabolizing enzymes [including alcohol dehydrogenase (ADH) and aldehyde dehydrogenase (ALDH)] was related to alcoholic brain atrophy, we determined restriction fragment-length polymorphisms of the ADH2 and ALDH2 genes in 77 male alcoholics. Computed tomography was used to...

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Source

Identifiers

PMID: 8659684
DOI: 10.1111/j.1530-0277.1996.tb01723.x

Genes

ALDH2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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