Article
Genotyping of alcohol dehydrogenase at the ADH2 and ADH3 loci by using a polymerase chain reaction and restriction-fragment-length polymorphism in Chinese alcoholic cirrhotics and non-alcoholics.
Proceedings of the National Science Council, Republic of China. Part B, Life sciences - 1 Jul 1994
Chao Y C, Wang M F, Tang H S, Hsu C T, Yin S J
Abstract excerpt
We investigated the genotype of ADH2 and ADH3 in Chinese alcoholic cirrhotics and non-alcoholics by using a polymerase chain reaction and restriction-fragment-length polymorphism. This method is non-radioactive, easy to implement with good reproducibility. In the Chinese population, the frequenci...
Topics
- Alcohol Dehydrogenase
- Alleles
- Base Sequence
- China
- Gene Frequency
- Genetic Predisposition to Disease
- Genotype
- Hepatitis, Viral, Human
- Humans
- Isoenzymes
- Liver Cirrhosis
- Liver Cirrhosis, Alcoholic
- Male
- Molecular Sequence Data