Association between severity of alcoholism and the A1 allele of the dopamine D2 receptor gene TaqI A RFLP in Japanese.

doi:10.1016/0006-3223(93)90309-2

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Article

Association between severity of alcoholism and the A1 allele of the dopamine D2 receptor gene TaqI A RFLP in Japanese.

Biological psychiatry - 15 Jan 1993

Arinami T, Itokawa M, Komiyama T, Mitsushio H, Mori H, Mifune H, Hamaguchi H, Toru M

Abstract excerpt

The allelic association of TaqI A restriction fragment length polymorphism (RFLP) of the dopamine D2 receptor gene with alcoholism was examined in 78 Japanese alcoholics and compared with Japanese controls. A significantly higher frequency of the A1 allele (0.42) was found in 100 Japanese unscree...

Topics

Age Factors
Aged
Alcoholism
Alleles
Female
Genotype
Humans
Japan
Male
Middle Aged
Polymorphism, Restriction Fragment Length
Racial Groups
Receptors, Dopamine
Severity of Illness Index

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