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Article

Two genes abrogate the inhibition of murine hepatocarcinogenesis by ovarian hormones.

Proceedings of the National Academy of Sciences of the United States of America - 11 Jun 1996

Poole T M, Drinkwater N R

Abstract excerpt

Hormonal and genetic factors strongly influence the susceptibility of inbred mice to hepatocarcinogenesis. Female C57BR/cdJ (BR) mice are extremely susceptible to liver tumor induction relative to other strains because they are genetically insensitive to the inhibition of hepatocarcinogenesis by...

Topics

Animals
Chromosome Mapping
Crosses, Genetic
Female
Genetic Linkage
Genetic Markers
Genetic Predisposition to Disease
Gonadal Steroid Hormones
Liver Neoplasms, Experimental
Male
Mice
Mice, Inbred C57BL

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Ovary

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Identifiers

PMID: 8650181
DOI: 10.1073/pnas.93.12.5848
PMCID: PMC39150

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-8650181-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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