Strain-dependent differences in DNA synthesis and gene expression in the regenerating livers of CB57BL/6J and C3H/HeJ mice.

doi:10.1002/mc.2940140109

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Article

Strain-dependent differences in DNA synthesis and gene expression in the regenerating livers of CB57BL/6J and C3H/HeJ mice.

Molecular carcinogenesis - 1 Sept 1995

Bennett L M, Farnham P J, Drinkwater N R

Abstract excerpt

C3H/HeJ (C3H) mice are approximately 50-fold more susceptible to liver-tumor induction than C57BL/6J (B6) mice. This difference is susceptibility is a consequence of allelic differences in hepatocarcinogen sensitivity (Hcs) genes that control the growth of preneoplastic lesions in the liver. We h...

Topics

Animals
Blotting, Northern
Carcinogens
DNA
Gene Expression
Genes, fos
Genetic Predisposition to Disease
Glyceraldehyde-3-Phosphate Dehydrogenases
Hepatectomy
Kinetics
Liver
Liver Neoplasms

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Liver Neoplasms, Experimental

Liver Regeneration

Mice

Mice, Inbred C3H

Mice, Inbred C57BL

Precancerous Conditions

Source

Open in PubMed

Identifiers

PMID: 7546224
DOI: 10.1002/mc.2940140109

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-7546224-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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