The Hcr (hepatocarcinogen resistance) loci of DBA/2J mice partially suppress phenotypic expression of the Hcs (hepatocarcinogen sensitivity) loci of C3H/HeJ mice.

doi:10.1093/carcin/16.8.1993

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Article

The Hcr (hepatocarcinogen resistance) loci of DBA/2J mice partially suppress phenotypic expression of the Hcs (hepatocarcinogen sensitivity) loci of C3H/HeJ mice.

Carcinogenesis - 1 Aug 1995

Lee G H, Drinkwater N R

Abstract excerpt

Both male DBA/2J and C3H/HeJ mice are highly susceptible to hepatocarcinogenesis induced by experimental treatment with N,N-diethylnitrosamine (DEN) relative to male C57BL/6J mice. While C3H/HeJ mice carry multiple sensitivity loci, designated Hcs (hepatocarcinogen sensitivity), our previous stud...

Topics

Animals
Chromosome Mapping
Diethylnitrosamine
Glycogen Storage Disease Type I
Liver Neoplasms, Experimental
Male
Mice
Mice, Inbred C3H
Mice, Inbred C57BL
Mice, Inbred DBA
Phenotype

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