Article
Predominant modifier of extreme liver cancer susceptibility in C57BR/cdJ female mice localized to 6 Mb on chromosome 17.
Carcinogenesis - 1 May 2009
Peychal Stephanie E-M, Bilger Andrea, Pitot Henry C, Drinkwater Norman R
Abstract excerpt
Sex hormones influence the susceptibility of inbred mice to liver cancer. C57BR/cdJ (BR) females are extremely susceptible to spontaneous and chemically induced liver tumors, in part due to a lack of protection against hepatocarcinogenesis normally offered by ovarian hormones. BR males are also moderately susceptible, and the susceptibility of both sexes of BR mice to liver tumors induced with...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
