Article
Hepatocarcinogenesis in BXH recombinant inbred strains of mice: analysis of diverse phenotypic effects of the hepatocarcinogen sensitivity loci.
Molecular carcinogenesis - 1 Nov 1995
Lee G H, Drinkwater N R
Abstract excerpt
The hepatocarcinogen sensitivity (Hcs) loci were originally identified as determinants of the approximately 50-fold higher susceptibility of male C3H/HeJ (C3H) mice to perinatally induced hepatocarcinogenesis relative to male C57BL/6J (B6) mice. These two inbred strains also differ in other phenotypes related to hepatocarcinogenesis, including their incidences of spontaneous liver tumors and the properties of...
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