Multiple loci affect genetic predisposition to hepatocarcinogenesis in mice.

doi:10.1006/geno.1994.1466

Back to search

Article

Multiple loci affect genetic predisposition to hepatocarcinogenesis in mice.

Genomics - 1 Sept 1994

Manenti G, Binelli G, Gariboldi M, Canzian F, De Gregorio L, Falvella F S, Dragani T A, Pierotti M A

Abstract excerpt

The C3H/He mouse represents a good experimental model of genetic predisposition to hepatocellular tumor development. We analyzed an interspecific test-cross population of 106 urethane-treated male (C3H/He x Mus spretus) x C57BL/6J mice, typed with 222 genetic markers to locate precisely the hepat...

Topics

Animals
Chromosome Mapping
Crosses, Genetic
Genetic Linkage
Genetic Predisposition to Disease
Liver Neoplasms, Experimental
Male
Mice
Mice, Inbred A
Mice, Inbred C3H
Mice, Inbred C57BL
Muridae
Urethane

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

discussions

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.