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Article

Multiple loci affect genetic predisposition to hepatocarcinogenesis in mice.

Genomics - 1 Sept 1994

Manenti G, Binelli G, Gariboldi M, Canzian F, De Gregorio L, Falvella F S, Dragani T A, Pierotti M A

Abstract excerpt

The C3H/He mouse represents a good experimental model of genetic predisposition to hepatocellular tumor development. We analyzed an interspecific test-cross population of 106 urethane-treated male (C3H/He x Mus spretus) x C57BL/6J mice, typed with 222 genetic markers to locate precisely the hepatocellular tumor susceptibility (Hcs) loci. Three regions, on chromosomes 2, 5, and 19, showed a significant linkage...

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Source

Identifiers

PMID: 7829059
DOI: 10.1006/geno.1994.1466

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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