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Article

Rod phototransduction in transgenic mice expressing a mutant opsin gene.

Journal of the Optical Society of America. A, Optics, image science, and vision - 1 Mar 1996

Goto Y, Peachey N S, Ziroli N E, Seiple W H, Gryczan C, Pepperberg D R, Naash M I

Abstract excerpt

Rod-mediated electroretinograms (ERG's) were recorded from transgenic mice expressing a mouse opsin gene with three point mutations (V20G, P23H, and P27L; termed VPP mice) and from normal littermates. The leading edge of the alpha wave was analyzed in relation to a computational model of rod phototransduction [J. Physiol. 499, 719 (1992)], in which values for the maximum response (RmP3), transduction gain (S),...

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Identifiers

PMID: 8627415
DOI: 10.1364/josaa.13.000577

Genes

ERG

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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