Article

Visual system hyperexcitability and compromised V1 receptive field properties in early-stage retinitis pigmentosa in mice

2022-05-16

Abstract excerpt

Inherited retinal degenerative diseases are a prominent cause of blindness. Even though mutations causing death of photoreceptors are mostly known, the pathophysiology downstream in the inner retina and along the visual pathway is incompletely characterized in the earliest disease stages. Here we investigated retinal, midbrain and cortical visual function using electroretinography (ERG), the optomotor response (OM...

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Literature Corpus work: 686df66e-1b0c-57ed-938d-7807309ff2ec
DOI: 10.1101/2022.05.16.492079

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