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Article

Modulation of phosphodiesterase6 turnoff during background illumination in mouse rod photoreceptors.

The Journal of neuroscience : the official journal of the Society for Neuroscience - 27 Feb 2008

Woodruff Michael L, Janisch Kerstin M, Peshenko Igor V, Dizhoor Alexander M, Tsang Stephen H, Fain Gordon L

Abstract excerpt

In rod photoreceptors of wild-type mice, background light produces an acceleration of the decay of responses to brief flashes, accompanied by a decrease in the rate-limiting time constant for response decay. In rods in which phosphodiesterase gamma (PDEgamma) lacks one of its sites of phosphorylation (T35A rods), both the waveform of response decay and the rate-limiting time constant are nearly unaffected by...

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Share to Adaptation, Ocular
Share to Cyclic Nucleotide Phosphodiesterases, Type 6

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Share to Dose-Response Relationship, Radiation

Share to Evoked Potentials

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Share to Retinal Rod Photoreceptor Cells

Source

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Identifiers

PMID: 18305241
DOI: 10.1523/JNEUROSCI.2973-07.2008
PMCID: PMC2750778

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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