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Article

Transgenic ablation of rod photoreceptors alters the circadian phenotype of mice.

Neuroscience - 1 Mar 1999

Lupi D, Cooper H M, Froehlich A, Standford L, McCall M A, Foster R G

Abstract excerpt

The impact of photoreceptor loss on the circadian system was examined by utilizing a transgenic mouse model (rdta) in which rod photoreceptors were specifically ablated. These mice were able to phase-shift their circadian locomotor behaviour in response to light, but features of this circadian behaviour were markedly altered. The amplitude of circadian responses to light were approximately 2.5 greater, the...

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Identifiers

PMID: 10077319
DOI: 10.1016/s0306-4522(98)00353-4

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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