Article
Implication of the BRCA2 and putative "BRCA3" genes in Dukes' stage C, replication error-negative colon cancer.
Annals of surgical oncology - 1 Jun 2006
Sivarajasingham Nala S, Cawkwell Lynn, Baker Richard P, O'Kane Sara L, Smyth Edward F, Tilsed Jonathan V T, Watson Mark B, Greenman John, Monson John R T
Abstract excerpt
BACKGROUND: Although BRCA genes have been implicated in certain tumors, particularly breast tumors, their role in colon tumorigenesis has not been fully explored. We aimed to investigate the association of the BRCA2 and putative "BRCA3" genes in a homogeneous series of right-sided colon cancer specimens. METHODS: Twenty-three Dukes' stage C, replication error-negative carcinomas were selected from patients with...
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