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Article

Microsatellite instability and p53 mutations in sporadic right and left colon carcinoma: different clinical and molecular implications.

Cancer - 1 Sept 1998

Lleonart M E, García-Foncillas J, Sánchez-Prieto R, Martín P, Moreno A, Salas C, Ramón y Cajal S

Abstract excerpt

BACKGROUND: Left and right colon carcinomas can display different clinical, pathologic, and genetic characteristics. The purpose of this study was to characterize multiple molecular genetic alterations in sporadic colon carcinoma and to correlate them with the location of the tumors and with lymph node metastasis. METHODS: One hundred and twenty-five cases of sporadic colon carcinoma (50 in the right colon and 75...

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PMID: 9731891

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