Article
Identifying a region of interest in site- and stage-specific colon cancer on chromosome 13.
Annals of surgical oncology - 1 Nov 2003
Sivarajasingham Nala S, Baker Richard, Tilsed Jonathan V, Greenman John, Monson John R T, Cawkwell Lynn
Abstract excerpt
BACKGROUND: The role of genes on chromosome 13q has not been confirmed in colorectal tumors, in part because most series that have been studied are heterogeneous in terms of tumor site, stage, and replication error (RER) status. Using a highly homogenous series of colon tumors, our aim was to identify areas of interest on 13q that are important in carcinogenesis. METHODS: Twenty-three RER-negative tumor specimens...
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