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Article

Interaction between Wingless and Notch signaling pathways mediated by dishevelled.

Science (New York, N.Y.) - 29 Mar 1996

Axelrod J D, Matsuno K, Artavanis-Tsakonas S, Perrimon N

Abstract excerpt

In Drosophila, the Wingless and Notch signaling pathways function in m any of the same developmental patterning events. Genetic analysis demonstrates that the dishevelled gene, which encodes a molecule previously implicated in implementation of the Winglass signal, interacts antagonistically with Notch and one of its known ligands, Delta. A direct physical interaction between Dishevelled and the Notch carboxyl...

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Identifiers

PMID: 8596950
DOI: 10.1126/science.271.5257.1826

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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