Article
The Drosophila segment polarity gene dishevelled encodes a novel protein required for response to the wingless signal.
Genes & development - 1 Jan 1994
Klingensmith J, Nusse R, Perrimon N
Abstract excerpt
The Drosophila Wnt-1 homolog, wingless (wg), is involved in the signaling of patterning information in several contexts. In the embryonic epidermis, Wg protein is secreted and taken up by neighboring cells, in which it is required for maintenance of engrailed transcription and accumulation of Arm...
Topics
- Adaptor Proteins, Signal Transducing
- Amino Acid Sequence
- Animals
- Base Sequence
- Cell Polarity
- DNA
- Dishevelled Proteins
- Drosophila
- Drosophila Proteins
- Embryonic Induction
- Female
- Male
- Molecular Sequence Data
- Phenotype
- Phosphoproteins
- Proteins
- Proto-Oncogene Proteins
- Restriction Mapping