Article
The Drosophila segment polarity gene dishevelled encodes a novel protein required for response to the wingless signal.
Genes & development - 1 Jan 1994
Klingensmith J, Nusse R, Perrimon N
Abstract excerpt
The Drosophila Wnt-1 homolog, wingless (wg), is involved in the signaling of patterning information in several contexts. In the embryonic epidermis, Wg protein is secreted and taken up by neighboring cells, in which it is required for maintenance of engrailed transcription and accumulation of Armadillo protein. The dishevelled (dsh) gene mediates these signaling events as well as wg-dependent induction across...
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