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Article

Dapper, a Dishevelled-associated antagonist of beta-catenin and JNK signaling, is required for notochord formation.

Developmental cell - 1 Apr 2002

Cheyette Benjamin N R, Waxman Joshua S, Miller Jeffrey R, Takemaru Ken-Ichi, Sheldahl Laird C, Khlebtsova Natasha, Fox Eric P, Earnest Thomas, Moon Randall T

Abstract excerpt

Dapper was isolated in a screen for proteins interacting with Dishevelled, a key factor in Wnt signaling. Dapper and Dishevelled colocalize intracellularly and form a complex with Axin, GSK-3, CKI, and beta-catenin. Overexpression of Dapper increases Axin and GSK-3 in this complex, resulting in d...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 11970895
DOI: 10.1016/s1534-5807(02)00140-5

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-11970895-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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