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Article

Apolipoprotein E4 promotes incipient Alzheimer pathology in the elderly.

Alzheimer disease and associated disorders - 1 Mar 1998

Warzok R W, Kessler C, Apel G, Schwarz A, Egensperger R, Schreiber D, Herbst E W, Wolf E, Walther R, Walker L C

Abstract excerpt

To evaluate the influence of the apolipoprotein E (ApoE) epsilon4 allele on the age at which Alzheimer-like lesions appear in the brain, we analyzed the degree of cerebral beta-amyloidosis and neurofibrillary tangle formation in the hippocampal formation and adjacent cortical areas 28, 27, and 36 of persons who had died between the ages of 50 and 93 years and who had shown no signs of clinical dementia. The...

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Identifiers

PMID: 9539408
DOI: 10.1097/00002093-199803000-00005

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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