Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The apolipoprotein E epsilon 4 allele is associated with increased neuritic plaques and cerebral amyloid angiopathy in Alzheimer's disease and Lewy body variant.

Neurology - 1 Jul 1996

Olichney J M, Hansen L A, Galasko D, Saitoh T, Hofstetter C R, Katzman R, Thal L J

Abstract excerpt

OBJECTIVE: To determine the relationship between apolipoprotein E (apoE) genotype and neuropathologic lesions in Alzheimer's disease (AD) and Lewy body variant (LBV). DESIGN: Retrospective genetic-neuropathologic study of AD and LBV cases. The main neuropathologic outcome measures were modeled as a function of apoE genotype, neuropathologic diagnosis, and gender. Age at death and duration of symptom effects were...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Aged
Share to Aged, 80 and over

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Alzheimer Disease

Share to Analysis of Variance

Share to Apolipoproteins E

Share to Cerebral Amyloid Angiopathy

Share to Genotype

Share to Lewy Bodies

Source

Identifiers

PMID: 8710076
DOI: 10.1212/wnl.47.1.190

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The apolipoprotein E epsilon 4 allele is associated with increased neuritic plaques and cerebral amyloid angiopathy in Alzheimer's disease and Lewy body variant.PMID 8710076Read ↗

APOE, vascular pathology, and the AD brain.Semantic proximity Read ↗

The apolipoprotein E allele epsilon 4 is overrepresented in patients with the Lewy body variant of Alzheimer's disease.Semantic proximity Read ↗

Apolipoprotein E epsilon 4 and cerebral hemorrhage associated with amyloid angiopathy.Semantic proximity Read ↗

Apolipoprotein E-epsilon4 alleles in cerebral amyloid angiopathy and cerebrovascular pathology associated with Alzheimer's disease.Semantic proximity Read ↗

Clinical and pathological correlates of apolipoprotein E epsilon 4 in Alzheimer's disease.Semantic proximity Read ↗

Impact of APOE genotype on neuropathologic and neurochemical markers of Alzheimer disease.Semantic proximity Read ↗

Apolipoprotein E epsilon4 allele, AD pathology, and the clinical expression of Alzheimer's disease.Semantic proximity Read ↗

Association of the apolipoprotein E epsilon 4 allele with clinical subtypes of autopsy-confirmed Alzheimer's disease.Semantic proximity Read ↗

APOE epsilon 4 influences the pathological phenotype of Alzheimer's disease by favouring cerebrovascular over parenchymal accumulation of A beta protein.Semantic proximity Read ↗

The apolipoprotein E epsilon4 allele frequency is normal in fronto-temporal dementia, but correlates with age at onset of disease.Semantic proximity Read ↗

Alzheimer pathology of patients carrying apolipoprotein E epsilon 4 allele.Semantic proximity Read ↗

Influence of apolipoprotein E genotype on senile dementia of the Alzheimer and Lewy body types. Significance for etiological theories of Alzheimer's disease.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.