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Article

The RB2/p130 gene product is a nuclear protein whose phosphorylation is cell cycle regulated.

Journal of cellular biochemistry - 1 Nov 1995

Baldi A, De Luca A, Claudio P P, Baldi F, Giordano G G, Tommasino M, Paggi M G, Giordano A

Abstract excerpt

The Rb2/p130 protein has been shown to have a high sequence homology with the retinoblastoma gene product (pRb), one of the most well-characterized tumor suppressor genes, and with pRB-related p107, especially in their conserved pocket domains, which display a primary role in the function of these proteins. In this study, we report on the biochemical and immunocytochemical characterization of the Rb2/p130...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 8567757
DOI: 10.1002/jcb.240590311

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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The RB2/p130 gene product is a nuclear protein whose phosphorylation is cell cycle regulated.PMID 8567757Read ↗

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Cdk phosphorylation triggers sequential intramolecular interactions that progressively block Rb functions as cells move through G1.Semantic proximity Read ↗

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Protein phosphatase 2A subunit PR70 interacts with pRb and mediates its dephosphorylation.Semantic proximity Read ↗

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