Article
Regulation of the MAP kinase cascade.
Cellular & molecular biology research - 1 Jan 1994
Cobb M H, Xu S, Hepler J E, Hutchison M, Frost J, Robbins D J
Abstract excerpt
The MAP kinase cascade is regulated by many hormones and growth factors and its activation leads to changes in properties of cytoplasmic, membrane-associated, and nuclear proteins. The MAP kinases themselves are activated by MEKS. MEKs lie at a point of convergence for multiple upstream signals,...
Topics
- Animals
- Binding Sites
- Calcium-Calmodulin-Dependent Protein Kinases
- Humans
- Mitogen-Activated Protein Kinase 1
- Mitogen-Activated Protein Kinase 3
- Mitogen-Activated Protein Kinases
- Molecular Structure
- Mutation
- Phosphorylation
- Protein Conformation
- Signal Transduction