Article
New eukaryotic transcriptional repressors.
Nature - 17 Jun 1993
Saha S, Brickman J M, Lehming N, Ptashne M
Abstract excerpt
Transcriptional activating sequences have been described that are encoded by parts of the genome of Escherichia coli. These acidic peptides, fused to a DNA-binding fragment of the yeast transcriptional activator GAL4, activate transcription of a gene in a wide array of eukaryotes, provided that gene bears GAL4-binding sites nearby. Here we describe an E. coli-encoded sequence that, when attached to the same...
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