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Article

Analysis of the role of TFIIE in transcriptional regulation through structure-function studies of the TFIIEbeta subunit.

The Journal of biological chemistry - 31 Jul 1998

Okamoto T, Yamamoto S, Watanabe Y, Ohta T, Hanaoka F, Roeder R G, Ohkuma Y

Abstract excerpt

The general transcription factor TFIIE plays important roles at two distinct but sequential steps in transcription as follows: preinitiation complex formation and activation (open complex formation), and the transition from initiation to elongation. The large subunit of human TFIIE (TFIIEalpha) binds to and facilitates the enzymatic functions of TFIIH, but TFIIE also functions independently from TFIIH. To...

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Identifiers

PMID: 9677423
DOI: 10.1074/jbc.273.31.19866

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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Related research

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Analysis of the role of TFIIE in transcriptional regulation through structure-function studies of the TFIIEbeta subunit.PMID 9677423Read ↗

Association of the winged helix motif of the TFIIEα subunit of TFIIE with either the TFIIEβ subunit or TFIIB distinguishes its functions in transcription.Semantic proximity Read ↗

The essential and multifunctional TFIIH complexSemantic proximity Read ↗

A novel zinc finger structure in the large subunit of human general transcription factor TFIIE.Semantic proximity Read ↗

Structural insight into the TFIIE-TFIIH interaction: TFIIE and p53 share the binding region on TFIIH.Semantic proximity Read ↗

Disruption of the interaction between TFIIAαβ and TFIIA recognition element inhibits RNA polymerase II gene transcription in a promoter context-dependent manner.Semantic proximity Read ↗

ChIP-seq analysis reveals genes regulated by TFIIE and association of TFIIE with various pathwaysSemantic proximity Read ↗

Stimulation of the XPB ATP-dependent helicase by the beta subunit of TFIIE.Semantic proximity Read ↗

The complete structure of the human TFIIH core complexSemantic proximity Read ↗

The role of XPB/Ssl2 dsDNA translocation processivity in transcription-start-site scanningSemantic proximity Read ↗

Function of Conserved Topological Regions within the Saccharomyces cerevisiae Basal Transcription Factor TFIIH.Semantic proximity Read ↗

Cleavage and proteasome-mediated degradation of the basal transcription factor TFIIA.Semantic proximity Read ↗

Tfb6, a previously unidentified subunit of the general transcription factor TFIIH, facilitates dissociation of Ssl2 helicase after transcription initiation.Semantic proximity Read ↗

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