Article
Analysis of the role of TFIIE in transcriptional regulation through structure-function studies of the TFIIEbeta subunit.
The Journal of biological chemistry - 31 Jul 1998
Okamoto T, Yamamoto S, Watanabe Y, Ohta T, Hanaoka F, Roeder R G, Ohkuma Y
Abstract excerpt
The general transcription factor TFIIE plays important roles at two distinct but sequential steps in transcription as follows: preinitiation complex formation and activation (open complex formation), and the transition from initiation to elongation. The large subunit of human TFIIE (TFIIEalpha) b...
Topics
- Animals
- DNA, Single-Stranded
- DNA-Binding Proteins
- Drosophila
- Drosophila Proteins
- Gene Expression Regulation
- Humans
- Kruppel-Like Transcription Factors
- Mutation
- Phosphorylation
- Promoter Regions, Genetic
- RNA Polymerase II
- Repressor Proteins
- Sequence Deletion
- Structure-Activity Relationship