Article
Suppression of tumorigenicity in temperature-sensitive mutants of embryonal carcinoma cells by induction of cell differentiation at non-permissive temperature.
International journal of cancer - 8 May 1993
Sumi T, Nishina Y, Kosaka M, Sakuda M, Nishimune Y
Abstract excerpt
The temperature-sensitive (ts) mutants of cell differentiation derived from the mouse teratocarcinoma cell line F9, when exposed to non-permissive temperature, undergo stem-cell differentiation concomitant with a transient retardation of cell-cycle progression. By incubating these mutant strains...
Topics
- Alkaline Phosphatase
- Animals
- Cell Adhesion
- Cell Differentiation
- Cell Division
- In Vitro Techniques
- Mice
- Mutation
- Plasminogen Activators
- Temperature
- Teratoma
- Tumor Cells, Cultured