tsJT16, a cell cycle ts mutant of rat fibroblast defective in early G0/G1 transition, fails to induce G1-cyclin and cdk2 genes after serum stimulation at the nonpermissive temperature.

doi:10.1247/csf.19.341

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Article

tsJT16, a cell cycle ts mutant of rat fibroblast defective in early G0/G1 transition, fails to induce G1-cyclin and cdk2 genes after serum stimulation at the nonpermissive temperature.

Cell structure and function - 1 Oct 1994

Ueohzono T, Tanida-Miyake E, Kato N, Ide T

Abstract excerpt

tsJT16 is a cell-cycle temperature-sensitive (ts) mutant derived from rat fibroblasts whose functional defect appears soon after the growth stimulation from G0 phase. In addition to c-fos, c-myc and ornithine decarboxylase gene, 7 primarily inducible genes, c-jun, KC, JE, 2F1, 2A9, egr-1, and egr-2, were further shown to be expressed after serum stimulation at both permissive and nonpermissive temperatures....

Topics

Animals
CDC2-CDC28 Kinases
Calcimycin
Cell Line
Cyclin G
Cyclin G1
Cyclin-Dependent Kinase 2
Cyclin-Dependent Kinases
Cyclins
Cycloheximide
Fibroblasts

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

G1 Phase

Gene Expression

Mutation

Ornithine Decarboxylase

Precipitin Tests

Protein Serine-Threonine Kinases

Proto-Oncogene Proteins c-fos

Source

Open in PubMed

Identifiers

PMID: 7850896
DOI: 10.1247/csf.19.341

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-7850896-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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tsJT16, a cell cycle ts mutant of rat fibroblast defective in early G0/G1 transition, fails to induce G1-cyclin and cdk2 genes after serum stimulation at the nonpermissive temperature.PMID 7850896Read ↗

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