Abrogation of wild-type p53 mediated growth-inhibition by nuclear exclusion.

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Article

Abrogation of wild-type p53 mediated growth-inhibition by nuclear exclusion.

Oncogene - 18 Apr 1996

Knippschild U, Oren M, Deppert W

Abstract excerpt

We used clone 6 cells (rat embryo fibroblasts transformed by the temperature sensitive mutant p53val135 and an activated H-ras-gene (Michalovitz et al., 1990)), growth arrested at 32 degrees C, as a model to analyse whether and how transformed cells, growth-arrested by an overexpressed wild-type...

Topics

Animals
Antigens, Polyomavirus Transforming
Base Sequence
Cell Division
Cell Line, Transformed
Cyclin-Dependent Kinase Inhibitor p21
Cyclins
Cycloheximide
Cytoplasm
Emetine
Fibroblasts
Gene Expression Regulation, Neoplastic

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Genes, p53

Genes, ras

Molecular Sequence Data

Mutation

Nuclear Proteins

Pheochromocytoma

Source

Open in PubMed

Identifiers

PMID: 8622896

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-8622896-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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