c-myc and p53 gene expression in the differentiation of temperature-sensitive mutants of teratocarcinoma F9 cells.

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Article

c-myc and p53 gene expression in the differentiation of temperature-sensitive mutants of teratocarcinoma F9 cells.

Oncogene - 1 Dec 1992

Kosaka M, Iwai S A, Nishina Y, Sumi T, Nishimune Y

Abstract excerpt

We have previously reported the isolation of several temperature-sensitive (ts) mutants of F9 cells. Further investigations showed that some mutants were induced to differentiate at non-permissive temperature of cell growth, accompanied by changes in the expression of various genes, whereas others were not. During the differentiation induced by shifting up to the non-permissive temperature, a rapid and transient...

Topics

Animals
Blotting, Northern
Cell Differentiation
Cell Division
Gene Expression
Genes, jun
Genes, myc
Genes, p53
Kinetics
Mice
Mutation
RNA, Messenger

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

RNA, Neoplasm

Temperature

Teratoma

Transcription, Genetic

Tumor Cells, Cultured

Tumor Suppressor Protein p53

Source

Open in PubMed

Identifiers

PMID: 1461650

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-1461650-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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