Article
Immortalization and characterization of a Sertoli cell line from the adult rat.
Biology of reproduction - 1 Dec 1995
Roberts K P, Banerjee P P, Tindall J W, Zirkin B R
Abstract excerpt
To facilitate investigations of the regulation of adult Sertoli cell function, we have established a Sertoli cell line from sexually mature Sprague-Dawley rats. The cells were immortalized with the temperature-sensitive mutant of the SV40 virus, tsA255. The tsA255 large T antigen is heat-labile a...
Topics
- Animals
- Apoptosis
- Bucladesine
- Cell Division
- Cell Line, Transformed
- Clusterin
- DNA
- Follicle Stimulating Hormone
- Glycoproteins
- Hot Temperature
- Keratins
- Male
- Molecular Chaperones
- Mutation
- RNA, Messenger
- Rats
- Rats, Sprague-Dawley
- Sertoli Cells