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Article

A tumorigenic murine Sertoli cell line that is temperature-sensitive for differentiation.

The American journal of pathology - 1 Oct 1993

Boekelheide K, Lee J W, Hall S J, Rhind N R, Zaret K S

Abstract excerpt

The Sertoli cell is the epithelial cell within the seminiferous tubule responsible for supporting germ cells. Most current in vitro studies of Sertoli cell function use primary cultures because of the limited number of available Sertoli cell lines. In addition, few in vivo models of Sertoli cell malignancy have been described. In this study, a tumorigenic Sertoli cell line was developed by infection of isolated...

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PMID: 8214009
PMCID: PMC1887074

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