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Article

Delimiting the location of the scrapie prion incubation time gene on chromosome 2 of the mouse.

Genetics - 1 Apr 1993

Carlson G A, Ebeling C, Torchia M, Westaway D, Prusiner S B

Abstract excerpt

Scrapie is a transmissible neurodegenerative disease caused by unusual pathogens called prions. The interval between inoculation and illness for experimental mouse scrapie is dramatically influenced by an incubation time gene (Prn-i) that is linked to Prn-p, the structural gene for prion protein (PrP). Although prion proteins from mouse strains with short and long scrapie incubation times differ by two amino...

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Identifiers

PMID: 8462855
DOI: 10.1093/genetics/133.4.979
PMCID: PMC1205414

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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