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Article

Investigation of mcp1 as a quantitative trait gene for prion disease incubation time in mouse.

Genetics - 1 Sept 2008

O'Shea Marie, Maytham Emma G, Linehan Jackie M, Brandner Sebastian, Collinge John, Lloyd Sarah E

Abstract excerpt

The genetic basis of prion disease incubation time is principally determined by polymorphisms in the prion protein gene, Prnp. However, it is now known that other genetic factors are important. Several quantitative trait loci (QTL) have been identified across the genome including a broad region of linkage on Mmu11. Monocyte chemoattractant protein 1 (MCP-1) maps to this region and has been associated with...

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Identifiers

PMID: 18716327
DOI: 10.1534/genetics.108.090894
PMCID: PMC2535705

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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