Article
Genetic and environmental factors modify bovine spongiform encephalopathy incubation period in mice.
Proceedings of the National Academy of Sciences of the United States of America - 19 Jun 2001
Manolakou K, Beaton J, McConnell I, Farquar C, Manson J, Hastie N D, Bruce M, Jackson I J
Abstract excerpt
The incubation period (IP) and the neuropathology of transmissible spongiform encephalopathies (TSEs) have been extensively used to distinguish prion isolates (or strains) inoculated into panels of inbred mouse strains. Such studies have shown that the bovine spongiform encephalopathy (BSE) agent...
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