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Article

The retinoic acid receptor beta (Rarb) region of Mmu14 is associated with prion disease incubation time in mouse.

PloS one - 6 Dec 2010

Grizenkova Julia, Akhtar Shaheen, Collinge John, Lloyd Sarah E

Abstract excerpt

In neurodegenerative conditions such as Alzheimer's and prion disease it has been shown that host genetic background can have a significant effect on susceptibility. Indeed, human genome-wide association studies (GWAS) have implicated several candidate genes. Understanding such genetic susceptibility is relevant to risks of developing variant CJD (vCJD) in populations exposed to bovine spongiform encephalopathy...

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Identifiers

PMID: 21151910
DOI: 10.1371/journal.pone.0015019
PMCID: PMC2997791

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