Article
Conservation of binding site geometry among p-azophenylarsonate-specific antibodies.
Journal of immunology (Baltimore, Md. : 1950) - 1 Mar 1993
Parhami-Seren B, Kussie P H, Strong R K, Margolies M N
Abstract excerpt
Murine A/J anti-p-azophenylarsonate mAb that express a dominant cross-reactive Id are encoded by a single set of germ-line VH and VL region genes. The crystal structure of the Fab of antibody 36-71, which uses this canonical set of genes but is somatically mutated, was previously determined. An Fab 36-71:phenylarsonate complex was modeled, identifying amino acid side chains that were proposed as contact residues...
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