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Article

Verification of a model of a F(ab) complex with phenylarsonate by oligonucleotide-directed mutagenesis.

Journal of immunology (Baltimore, Md. : 1950) - 1 Mar 1993

Sompuram S R, Sharon J

Abstract excerpt

A model of the combining site of a mouse antibody specific for p-azophenylarsonate was tested by oligonucleotide-directed mutagenesis of the proposed hapten-contacting residues, Arg96 in the L chain, and Asn35, Trp47, Tyr50, Ser95, and Tyr100b in the H chain. The affinity and relative affinity for p-azophenylarsonate-N-acetyl-L-tyrosine of mutant antibodies expressed in transfectomas were determined by...

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PMID: 8436817

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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