Article
Antigen-binding site anatomy and somatic mutations in antibodies that recognize different types of antigens.
Journal of molecular recognition : JMR - 1 Mar 2012
Raghunathan Gopalan, Smart Jason, Williams Joseph, Almagro Juan Carlos
Abstract excerpt
The number of antibody structures co-crystallized with their respective antigens has increased rapidly in the last few years, thus offering a formidable source of information to gain insight into the structure-function relationships of this family of proteins. We have analyzed here 140 unique middle-resolution to high-resolution (<3 Å) antibody structures, including 55 in complex with proteins, 39 with peptides,...
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