Article
Mutant p53 expression in prostate carcinoma.
The Prostate - 1 Jan 1993
Van Veldhuizen P J, Sadasivan R, Garcia F, Austenfeld M S, Stephens R L
Abstract excerpt
The expression of the mutant p53 tumor suppressor gene was evaluated in 33 human prostate carcinomas. Using an immunohistochemical method with monoclonal antibodies PAb 1801 and PAb 240, 26 (79%) tumors demonstrated positive immunostaining for mutant p53. Only areas of glandular tumor were positive, with adjacent stromal elements and areas of glandular hyperplasia being negative. The predominant staining pattern...
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