p53 oncogene mutations in three human prostate cancer cell lines.

doi:10.1002/pros.2990230206

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Article

p53 oncogene mutations in three human prostate cancer cell lines.

The Prostate - 1 Jan 1993

Carroll A G, Voeller H J, Sugars L, Gelmann E P

Abstract excerpt

p53 gene structure and chromosome 17p alleles were studied in the three human prostate cancer cell lines, LNCaP, DU-145, and PC-3. Our laboratory has two separate culture lines of the LNCaP human prostate cancer cells. One strain, LNCaP-GW, had a mutation in one of two alleles at position 273 (ar...

Topics

Base Sequence
Cell Line
Chromosomes, Human, Pair 17
Genes, p53
Humans
Male
Mutation
Polymorphism, Restriction Fragment Length
Prostatic Neoplasms
Ribonucleases
Tumor Cells, Cultured

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