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Article

Frequency and characterization of p53 mutations in primary and metastatic human prostate cancer.

International journal of cancer - 1 Mar 1994

Dinjens W N, van der Weiden M M, Schroeder F H, Bosman F T, Trapman J

Abstract excerpt

We have studied the frequency of mutations in the p53 gene in human prostate cancer. The investigated material consisted of 20 primary-tumor tissue specimens, obtained by transurethral resection and tissue specimens of 15 lymph-node metastases, obtained at total prostatectomy. The applied methods encompassed immunohistochemistry on frozen sections, using the monoclonal antibody PAb 1801, and single-strand...

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PMID: 8314337
DOI: 10.1002/ijc.2910560504

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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