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Article

Frequency and characterization of p53 mutations in primary and metastatic human prostate cancer.

International journal of cancer - 1 Mar 1994

Dinjens W N, van der Weiden M M, Schroeder F H, Bosman F T, Trapman J

Abstract excerpt

We have studied the frequency of mutations in the p53 gene in human prostate cancer. The investigated material consisted of 20 primary-tumor tissue specimens, obtained by transurethral resection and tissue specimens of 15 lymph-node metastases, obtained at total prostatectomy. The applied methods encompassed immunohistochemistry on frozen sections, using the monoclonal antibody PAb 1801, and single-strand...

Topics

Amino Acid Sequence
Antibodies, Monoclonal
Base Sequence
Codon
Gene Expression
Genes, p53
Humans
Immunohistochemistry
Lymphatic Metastasis
Male
Molecular Sequence Data

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Mutation

Polymerase Chain Reaction

Polymorphism, Genetic

Prostatic Neoplasms

Source

Identifiers

PMID: 8314337
DOI: 10.1002/ijc.2910560504

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