Article
p53 protein and gene alterations in pathological stage C prostate carcinoma.
The Journal of urology - 1 Aug 1997
Salem C E, Tomasic N A, Elmajian D A, Esrig D, Nichols P W, Taylor C R, Skinner D G, Roy-Burman P, Lieskovsky G, Cote R J
Abstract excerpt
PURPOSE: We determined the extent of p53 immunoreactivity in pathological stage C prostate cancer as well as its correlation to tumor grade, substage, recurrence and proliferation rate. To define better the temporal relationship of p53 nuclear reactivity in prostate cancer p53 immunoreactivity was evaluated in all associated prostatic intraepithelial neoplasia lesions. MATERIALS AND METHODS: Using...
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